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A Structure-Function Analysis Shows SARS-CoV-2 BA.2.86 Balances Antibody Escape and ACE2 Affinity

Chang Liu,Daming Zhou,Aiste Dijokaite-Guraliuc,Piyada Supasa,Helen M. E. Duyvesteyn,Helen M. Ginn,Muneeswaran Selvaraj,Alexander J. Mentzer,Raksha Das,Thushan I. de Silva,Thomas G. Ritter,Megan Plowright,Thomas A. H. Newman,Lizzie Stafford,Barbara Kronsteiner,Nigel Temperton,Yuan Lui,Martin Fellermeyer,Philip Goulder,Paul Klenerman,Susanna J. Dunachie,Michael I. Barton,Mikhail A. Kutuzov,Omer Dushek,Elizabeth E. Fry,Juthathip Mongkolsapaya,Jingshan Ren,David I. Stuart,Gavin R. Screaton

Cell Reports Medicine（2024）

Cited 7|Views29
Key words
BA.2.65,coronavirus,SARS-CoV-2,antigenic escape,virus structure,ACE2 binding,virus evolution,receptor binding
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