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Proinsulin C-peptide is a Major Source of HLA-DQ8 Restricted HIPs Recognized by Human Islet-Infiltrating CD4+ T Cells

Pushpak Bhattacharjee,Miha Pakusch,Matthew Lacorcia,Eleonora Tresoldi,Alan F. Rubin, Abby Foster, Laura King, Chris Y. Chiu,Thomas W. H. Kay,John A. Karas,Fergus J. Cameron,Stuart Mannering

PNAS NEXUS（2024）

Cited 0|Views12
Key words
type 1 diabetes,hybrid insulin peptides,islet-infiltrating CD4(+) T cells,neoepitopes
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