RhoG Facilitates a Conformational Transition in the Guanine Nucleotide Exchange Factor Complex DOCK5/ELMO1 to an Open State

Mutsuko Kukimoto-Niino,Kazushige Katsura,Yoshiko Ishizuka-Katsura,Chiemi Mishima-Tsumagari,Mayumi Yonemochi,Mio Inoue,Reiko Nakagawa,Rahul Kaushik,Kam Y. J. Zhang,Mikako Shirouzu

JOURNAL OF BIOLOGICAL CHEMISTRY（2023）

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Key words

electron microscopy (EM),guanine nucleotide exchange factor (GEF),protein structure,Rho (Rho GTPase),Ras‐related C3 botulinum toxin substrate 1 (Rac1),signal transduction,single particle analysis,surface plasmon resonance (SPR)

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