Lipid-encapsulated Mrna Encoding an Extended Serum Half-Life Interleukin-22 Ameliorates Metabolic Disease in Mice

Susanna Canali,Alexander W. Fischer,Mychael Nguyen, Karl Anderson, Lorna Wu,Anne-Renee Graham,Chiaowen Joyce Hsiao, Chinmayi Bankar, Nancy Dussault, Veronica Ritchie, Meagan Goodridge, Todd Sparrow, Allison Pannoni,Sze-Wah Tse, Vivienne Woo, Kaitlin Klovdahl,Jared Iacovelli,Eric Huang

Molecular Metabolism（2024）

Cited 0|Views17

Key words

interleukin-22,Lipid nanoparticle therapeutic,Messenger RNA,Metabolic disorders,Metabolic dysfunction-associated steatotic liver disease,Serum lipid parameters

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