Microenvironment Shapes Small-Cell Lung Cancer Neuroendocrine States and Presents Therapeutic Opportunities

Parth Desai,Nobuyuki Takahashi,Rajesh Kumar,Samantha Nichols,Justin Malin,Allison Hunt,Christopher Schultz,Yingying Cao,Desiree Tillo,Darryl Nousome,Lakshya Chauhan,Linda Sciuto,Kimberly Jordan,Vinodh Rajapakse,Mayank Tandon,Delphine Lissa,Yang Zhang,Suresh Kumar,Lorinc Pongor,Abhay Singh,Brett Schroder,Ajit Kumar Sharma,Tiangen Chang,Rasa Vilimas,Danielle Pinkiert,Chante Graham,Donna Butcher,Andrew Warner,Robin Sebastian, Mimi Mahon, Karen Baker, Jennifer Cheng, Ann Berger,Ross Lake,Melissa Abel,Manan Krishnamurthy,George Chrisafis,Peter Fitzgerald, Micheal Nirula,Shubhank Goyal,Devon Atkinson,Nicholas W. Bateman,Tamara Abulez,Govind Nair,Andrea Apolo,Udayan Guha,Baktiar Karim,Rajaa El Meskini,Zoe Weaver Ohler,Mohit Kumar Jolly,Alejandro Schaffer,Eytan Ruppin,David Kleiner,Markku Miettinen,G. Tom Brown,Stephen Hewitt,Thomas Conrads,Anish Thomas

CELL REPORTS MEDICINE（2024）

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Key words

small-cell lung cancer,tumor microenvironment,tumor heterogeneity,spatial transcriptomics,cancer-associated fibroblasts,intercellular communication,rapid research autopsy

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