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A Glia-Enriched Stem Cell 3D Model of the Human Brain Mimics the Glial-Immune Neurodegenerative Phenotypes of Multiple Sclerosis

Francesca Fagiani,Edoardo Pedrini,Stefano Taverna,Elena Brambilla,Valentina Murtaj,Paola Podini,Francesca Ruffini,Erica Butti, Clarissa Braccia,Annapaola Andolfo,Roberta Magliozzi,Lena Smirnova,Tanja Kuhlmann,Angelo Quattrini,Peter A. Calabresi,Daniel S. Reich,Gianvito Martino,Paola Panina-Bordignon,Martina Absinta

Cell Reports Medicine（2024）

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关键词
hiPSC,brain organoids,SOX10,oligodendrocytes,single-cell genomics,multiple sclerosis,glia-microglia axis,neuroinflammation
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