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Quantitation and Characterization of Serotype 6A Activation for Pneumococcal Conjugate Vaccine by Cryo-Em and SEC Methods

Mingxiang Lin,James Z. Deng,Giovanna Scapin, Yue Yuan,Yacob Gomez-Llorente,Weidong Tong,Richard Porambo, Jongrock Kong, Nori Ikemoto,Catherine Lancaster,Jason Kaelber,Michael Winters,Ping Zhuang

Vaccine（2024）

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Key words
Pneumococcal conjugate vaccine,Pneumococcal capsular polysaccharide 6A,Cryo-electron microscopy (Cryo-EM),Size-exclusion chromatography (SEC),Gold nanoparticle (AuNP) labeling
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