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Discovery of 2,4,6-Trisubstituted Pyrimidine Derivatives As Novel Potent Hiv-1 Nnrtis by Exploiting the Tolerant Region Ii of the Nnibp

Zhenzhen Zhou,Yanying Sun,Yanyang Qin,Na Wang,Fabao Zhao,Zhao Wang,Erik De Clercq,Christophe Pannecouque,Peng Zhan,Dongwei Kang,Xinyong Liu

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（2024）

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关键词
HIV-1,NNRTIs,DAPYs,6-Trisubstituted pyrimidine derivatives,Drug resistance
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