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Intermittent Clearance of P21-Highly-expressing Cells Extends Lifespan and Confers Sustained Benefits to Health and Physical Function

Binsheng Wang,Lichao Wang,Nathan S. Gasek,Chia-Ling Kuo, Jia Nie,Taewan Kim, Pengyi Yan, Junyu Zhu,Blake L. Torrance,Yueying Zhou,Lisa C. Flores,Colton Allen, Allison M. Andrade,Chun Guo,Rachel L. Cohn,Evan R. Jellison,Jenna M. Bartley,George A. Kuchel, Sheng Li,Tamar Pirtskhalava,Tamar Tchkonia,Sumit Yadav,Laura Haynes,James L. Kirkland,Yuji Ikeno,Ming Xu

Cell Metabolism（2024）

Cited 1|Views18
Key words
cellular senescence,morbidity compression,inflammation,frailty,aging
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