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Discovery of Potent HIV-1 NNRTIs by CuAAC Click-Chemistry-based Miniaturized Synthesis, Rapid Screening and Structure Optimization

Lanlan Jing,Gaochan Wu,Fabao Zhao,Xiangyi Jiang,Na Liu,Da Feng,Yanying Sun,Tao Zhang,Erik De Clercq,Christophe Pannecouque,Dongwei Kang,Xinyong Liu,Peng Zhan

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（2024）

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Key words
HIV-1,NNRTIs,NNIBP,CuAAC,Direct screening
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