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Design and Optimization of Selectivity-Tunable Toll-like Receptor 7/8 Agonists As Novel Antibody-Drug Conjugate Payloads

Akash M. Patel,Aarron Willingham,Alan C. Cheng,Daniela Tomazela,Eddie Bowman,Esther Kofman, Fan Zhang,Jianming Bao,Jillian R. Sanzone,Jonathan W. Choy,John A. Flygare,Jin-Hwan Han,Komal Pradhan,Madeleine Kieffer,Natalia Chernyak, Peyman Akbari,Ping Liu,Rimsha Mehmood,Saraswathi Naravula,Scott A. Hollingsworth,Bhagyashree Bhagwat,Simon B. Lang,W. Michael Seganish

Journal of Medicinal Chemistry（2024）

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