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The PARP Inhibitor Rucaparib Blocks SARS-CoV-2 Virus Binding to Cells and the Immune Reaction in Models of COVID-19

Henrietta Papp,Emese Toth,Judit Bovari-Biri,Krisztina Banfai,Peter Juhasz,Mohamed Mahdi,Lilian Cristina Russo,David Bajusz,Adrienn Sipos,Laszlo Petri, Tibor Viktor Szalai,Agnes Kemeny,Monika Madai,Anett Kuczmog,Gyula Batta,Orsolya Mozner,Dorottya Vasko,Edit Hirsch, Peter Bohus,Gabor Mehes,Jozsef Tozser,Nicola J. Curtin,Zsuzsanna Helyes,Attila Toth,Nicolas C. Hoch,Ferenc Jakab,Gyorgy M. Keseru,Judit E. Pongracz,Peter Bai

BRITISH JOURNAL OF PHARMACOLOGY（2024）

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关键词
ACE2,COVID-19,NF kappa B,rucaparib,SARS-CoV-2 RNA,SARS-COV-2 spike protein,viral lung inflammation
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