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Conformationally Constrained Isoquinolinones As Orally Efficacious Hepatitis B Capsid Assembly Modulators

Eugen F. Mesaros,Andrew G. Cole,Steven G. Kultgen,Nagraj Mani,Kristi Yi Fan,Benjamin J. Dugan,Andrzej Ardzinski,Kim Stever,Holly M. Micolochick Steuer,Ingrid Graves,Sunny Tang,Troy O. Harasym,Angela M. Lam,Emily P. Thi,Bruce D. Dorsey,Michael J. Sofia

ACS MEDICINAL CHEMISTRY LETTERS（2024）

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关键词
HBV capsid,CAMs,Conformational constraint,Antiviral activity,In vivo efficacy
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