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Gain-of-Function Variants in SMAD4 Compromise Respiratory Epithelial Function

Mark E. Lindsay,Eleanor R. Scimone, Joseph Lawton, Rashmi Richa,Lael M. Yonker,Yuanpu P. Di,Karen Buch, Wukun Ouyang,Xiulei Mo,Angela E. Lin,Hongmei Mou

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY（2025）

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Key words
Myhre syndrome,SMAD4 mutation,nasal epithelial basal cells,cell proliferation,mucociliary differentiation,innate immunity
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