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Design, Synthesis and FXR Partial Agonistic Activity of Anthranilic Acid Derivatives Bearing Aryloxy Moiety As Therapeutic Agents for Metabolic Dysfunction-Associated Steatohepatitis

Cong Chen, Xianghui Zhou, Wa Cheng, Xin Li, Bing Zhang, Jiaojiao Tu,Jieyun Meng,Yanfen Peng,Xiaoqun Duan,Qiming Yu,Xiangduan Tan

BIOORGANIC CHEMISTRY(2024)

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关键词
Farnesoid X receptor,Partial agonists,Metabolic dysfunction-associated steatohepati-,tis,MASH,Bile acid,Anthranilic acid derivative,Hybrid
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