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Decreased Lipidated ApoE-receptor Interactions Confer Protection Against Pathogenicity of ApoE and Its Lipid Cargoes in Lysosomes

Jing L. Guo, Dylan Braun, Gabriel A. Fitzgerald, Yun-Ting Hsieh,Lionel Rouge,Alexandra Litvinchuk,Micah Steffek,Nicholas E. Propson, Catherine M. Heffner, Claire Discenza, Suk Ji Han,Anil Rana,Lukas L. Skuja, Bi Qi Lin,Elizabeth W. Sun,Sonnet S. Davis, Srijana Balasundar,Isabel Becerra,Jason C. Dugas,Connie Ha,Jennifer Hsiao-Nakamoto, Fen Huang, Shourya Jain, Jennifer E. Kung,Nicholas P. D. Liau,Cathal S. Mahon,Hoang N. Nguyen,Nathan Nguyen, Madhuja Samaddar, Yajuan Shi,David Tatarakis, Yuxi Tian, Yuda Zhu,Jung H. Suh,Thomas Sandmann,Meredith E. K. Calvert,Annie Arguello,Lesley A. Kane,Joseph W. Lewcock,David M. Holtzman, Christopher M. Koth, Gilbert Di Paolo

CELL(2025)

Cited 0|Views5
Key words
apolipoprotein E,low-density lipoprotein,cholesterol,arachidonate,high-density lipoprotein,PUFA,lipofuscin,Christchurch,induced pluripotent stem cells
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