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Extending the Time Window for Tenecteplase by Effective Reperfusion of Penumbral Tissue in Patients with Large Vessel Occlusion: Rationale and Design of a Multicenter, Prospective, Randomized, Open-Label, Blinded-Endpoint, Controlled Phase 3 Trial.

Vignan Yogendrakumar,Bruce C. Campbell,Leonid Churilov,Carlos Garcia-Esperon,Philip M. C. Choi,Dennis J. Cordato,Prodipta Guha,Gagan Sharma,Chushuang Chen,Amy Mcdonald,Vincent Thijs,Abul Mamun,Angela Dos Santos,Anna H. Balabanski,Timothy J. Kleinig,Ken S. Butcher,Michael J. Devlin,Fintan O'Rourke,Geoffrey A. Donnan,Stephen M. Davis,Christopher R. Levi,Henry Ma,Mark W. Parsons, ETERNAL-LVO Investigators

INTERNATIONAL JOURNAL OF STROKE（2024）

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Key words
Acute stroke therapy,ischemic stroke,treatment,tPA,thrombolysis,TNK
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