Type I IFN Induces Long-Chain Acyl-Coa Synthetase 1 to Generate a Phosphatidic Acid Reservoir for Lipotoxic Saturated Fatty Acids

Shelley Barnhart,Masami Shimizu-Albergine, Eyal Kedar,Vishal Kothari,Baohai Shao,Melissa Krueger,Cheng-Chieh Hsu,Jingjing Tang,Jenny E. Kanter,Farah Kramer,Danijel Djukovic,Vadim Pascua,Yueh-Ming Loo,Lucrezia Colonna, Sadie J. Van den Bogaerde,Jie An,Michael Gale Jr,Karen Reue,Edward A. Fisher,Sina A. Gharib, Keith B. Elkon,Karin E. Bornfeldt

JOURNAL OF LIPID RESEARCH（2025）

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Key words

Bis[monoacylglycerol]phosphates,enzymology/Enzyme mechanisms,glycerophospholipids,inflammation,lipotoxicity,macrophage,phospholipids/ phosphatidic acid

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