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Investigating the C2 Modulation of the Imidazo[1,2-a]pyrazine-Based Hit Compound CTN1122: Synthesis, in Vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition

Lhana Tisseur,Sandrine Cojean, Khadidiatou Gassama,Cedric Loge,Fabrice Pagniez,Christian Cave,Guillaume Bernadat,Philippe M. Loiseau,Stephane Bach, Jerome Thiefaine,Carine Picot,Christophe Tomasoni,Olivier Leclercq,Blandine Baratte,Thomas Robert,Patrice Le Pape,Najma Rachidi,Marc-Antoine Bazin,Pascal Marchand

CHEMMEDCHEM（2025）

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关键词
antileishmanial agents,imidazo[1,2-<italic>a</italic>]pyrazine,casein kinase 1,L-CK1.2 inhibitors,Suzuki-Miyaura coupling of heterocyclic triflates
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