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Discovery of SET Domain-Binding Primary Alkylamine-Tethered Degraders for the Simultaneous Degradation of NSD2-Long and RE-IIBP Isoforms

Linghao Hu,Hesong Xu,Ye Xu, Haowen Chen, Hanrui Jiang, Dounan Xu,Huimin Zhang,Cheng Luo,Shijie Chen,Mingliang Wang

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY（2025）

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Key words
NSD2,RE-IIBP,Targeted protein degradation,Multiple myeloma
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