ZAR1/2-Regulated Epigenetic Modifications Are Essential for Age-Associated Oocyte Quality Maintenance and Zygotic Activation

Yan Rong,Yu-Ke Wu, Yingyan Chen, Qing Liu, Leilei Ai, Yun-Wen Wu,Yezhang Zhu, Yin-Li Zhang, Chengkan Liu,Yerong Ma,Xiaomei Tong, Jiamin Jin, Xiaoxuan Li, Yan Zhou, Shu-Yan Ji,Songying Zhang,Heng-Yu Fan

ADVANCED SCIENCE（2025）

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Key words

histone modifications,maternal factor,oocyte epigenetic maturation,oocyte-to-embryo transition,reproductive aging

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