Development and Validation of the Nomogram of High Fascial Compartment Pressure with Pilon Fracture

Xin Hu, Peiyuan Wang, Chengsi Li, Lin Liu,Xin Wang,Lin Jin,Kuo Zhao,Ling Wang,Zhiyong Hou

International Orthopaedics（2025）

The Third Hospital of Hebei Medical University | Orthopaedic Research Institute of Hebei Province

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Abstract

High Fascial Compartment Pressure (HCP) is one of the most common complications in ankle fractures. This study aimed to investigate the incidence of HCP in pilon fracture and analyze the risk factors of HCP in order to closely monitor its further development into Acute Compartment Syndrome. A nomogram is constructed and validated to predict HCP in patients with pilon fracture. We collected information on 1,863 patients with pilon fracture in the 3rd Hospital of Hebei Medical University Hospital from January 2019 to March 2024. Patients with HCP were assigned to the HCP group and those without HCP to the non-HCP group. The inpatient medical record system was inquired for data collection, including demographics, comorbidities, injury types, and laboratory biomarkers. Variables with a significance level of P < 0.05 in the univariate analysis were included in the multivariate logistic regression analysis. The backward stepwise regression method was applied to identify independent risk factors associated with HCP. The selected predictors were then entered into R software for further analysis, and Nomogram construction. The rate of HCP was 11.57

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Key words

High fascial compartment pressure,Acute compartmental syndrome,Pilon fracture,Predictors,Nomogram,Systemic immune-inflammation index

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