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Engineered Ipilimumab Variants That Bind Human and Mouse CTLA-4

Brett Robison, S. J. Diong, Anusha Kumar, Thomas M. Moon, Olin Chang,Bryant Chau,Christine Bee,Ishita Barman,Arvind Rajpal,Alan J. Korman, Sean West,Pavel Strop,Peter S. Lee

MABS(2025)

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关键词
Antibody engineering,CTLA-4,immune checkpoint,phage display,species cross reactivity,yeast display
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