Application of an Interdisciplinary Approach to Form Selection in Drug Development

Darren L. Reid, Margaret M. Faul, Vilmalí López-Mejías, Prashant Agarwal, Markus Bergauer,Laura E. Blue,Mary K. Chaves, John Chung, Melanie Cooke,Robert P. Farrell, James E. Huckle,Ron C. Kelly,Y.-H. Kiang, Weikun Li, Adrian Ortiz, Qiong Wu

Organic Process Research & Development（2025）

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Key words

active pharmaceutical ingredient,development form,physical and chemical stability,solubility,form screen,form selection,polymorph,salt,cocrystal,drug substance,drug product,solid-state properties,biopharmaceutical performance,processability and manufacturability,high-throughput,critical material attributes,target product profile,dosage form,biopharmaceutical classification system

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