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A Comprehensive Benchmarking for Evaluating TCR Embeddings in Modeling TCR-epitope Interactions.

Xikang Feng,Miaozhe Huo, He Li, Yongze Yang,Yuepeng Jiang, Liang He,Shuai Cheng Li

BRIEFINGS IN BIOINFORMATICS(2025)

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Key words
TCR-epitope interaction,benchmarking TCR CDR3 encoding,biological relevance of embeddings,data-driven and handcrafted embeddings
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