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Rare Twin Cysteine Residues in the HIV-1 Envelope Variable Region 1 Link to Neutralization Escape and Breadth Development

Maria C. Hesselman,Marius Zeeb,Peter Rusert,Chloé Pasin, Jennifer Mamrosh, Samuel Kariuki,Ian Pichler, Michèle Sickmann, Masako M. Kaufmann,Daniel Schmidt,Nikolas Friedrich,Karin J. Metzner, Audrey Rindler,Herbert Kuster,Craig Adams,Ruwayhida Thebus,Michael Huber,Sabine Yerly,Karoline Leuzinger,Matthieu Perreau

Cell Host & Microbe（2025）

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关键词
HIV vaccine,envelope glycoprotein,broadly neutralizing antibodies,elite neutralizers,V1V2,Env stabilization
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