SPP1 Promotes NSCLC Brain Metastasis Via Sequestration of Ubiquitin Ligase RNF114 to Facilitate P85α Ubiquitination

Xiaoqin Li, Yun Wu,Baosong Xie, Mingxiao Xu, Tianjian Xie,Wenxiang Yue, Ming Lin, Ying Lin,Yusheng Chen

MOLECULAR CARCINOGENESIS（2025）

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关键词

brain metastasis,NSCLC,P85 alpha,PI3K/AKT/mTOR pathway,RNF114,SPP1,ubiquitination

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