Identifying Distinct Prognostic and Predictive Contributions of Tumor Epithelium Versus Tumor Microenvironment in Colorectal Cancer

Mingli Yang, Michael V. Nebozhyn,Michael J. Schell,Nishant Gandhi,Lance Pflieger,Andrey Loboda,W. Jack Pledger, Ramani Soundararajan,Michelle Maurin,Heiman Wang, Jetsen Rodriguez Silva, Ashley Alden,Domenico Coppola,Andrew Elliott,George Sledge,Moh’d Khushman,Emil Lou,Sanjay Goel,Timothy J. Yeatman

BMC Cancer（2025）

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Key words

Colorectal cancer,Consensus molecular subtype,Clinical outcome,Tumor epithelium,Tumor microenvironment,Gene expression signature,EGFR inhibitor,Cetuximab,Panitumumab,MEK inhibitor

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