An Integrated Machine Learning Model of Transcriptomic Genes in Multi-Center Chronic Obstructive Pulmonary Disease Reveals the Causal Role of TIMP4 in Airway Epithelial Cell

Erkang Yi, Haiqing Li, Yu Liu, Qingyang Li, Chengshu Xie, Ruining Sun,Fan Wu, Zhishan Deng, Kunning Zhou, Hairong Wang, Xinru Ran,Yumin Zhou,Pixin Ran

Respiratory Research（2025）

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Key words

Chronic obstructive pulmonary disease,Machine learning,Mendelian randomization,Matrix metallopeptidase 4

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