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Structure-Based Design and Optimization Lead to the Identification of a Novel Potent Seh Inhibitor with PPARγ Partial Agonist Activity Against Inflammatory and Metabolic-Related Diseases.

Ruolin Cao,Maoying Zhang, Minggang Qi, Zhen Zhang,Christophe Morisseau, Chunwei Zhou, Tianqi Sun, Junning Zhuang,Lu Chen, Cheng Xu,Zhongbo Liu, Bruce D Hammock,Guoliang Chen

Journal of medicinal chemistry（2025）

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