Characterizing Spatial Immune Architecture in Metastatic Melanoma Using High-Dimensional Multiplex Imaging

Joel Eliason, Santhoshi Krishnan, Yasunari Fukuda,Matias A Bustos, Dan Winkowski, Sungnam Cho, Akshay Basi, Regan Baird, Elizabeth A Grimm,Michael A Davies,Dave S B Hoon,Arvind Rao,Jared K Burks,Suhendan Ekmekcioglu

Frontiers in immunology（2025）

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Key words

tumor immune microenvironment (TIME),immune exclusion,spatial immune profiling,inflammatory biomarkers,melanoma progression,prognostic immune signatures

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