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CRISPR Screens Identify POLB As a Synthetic Lethal Enhancer of PARP Inhibition Exclusively in BRCA-mutated Tumors.

Katherine Lazarides, Justin L Engel, Michele Meseonznik, Tianshu Feng, Ashley H Choi,Yi Yu, Shangtao Liu, Samuel R Meier, Hongxiang Zhang,Binzhang Shen, Robert Tjin Tham Sjin,Douglas A Whittington, Brian J McMillan, Brian Doyon,Xuewen Pan,Erik Wilker,Alan Huang,Jannik N Andersen, William D Mallender, Madhavi Bandi

Molecular cancer therapeutics(2025)

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