Dose-dependent Immunotoxic Mechanisms of Celastrol Via Modulation of the PI3K-Akt Signaling Pathway

Shaohui Geng, Jingqi Wen, Chunli Shen, Li Liu, Yijin Jiang, Jingyuan Fu, Yiwei Guan, Zi Ye,Yuanhao Wu,Chen Li,Guangrui Huang

Frontiers in pharmacology（2025）

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celastrol,immunotoxicity,PI3K-Akt signaling pathway,network toxicology,molecular docking

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