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Discovery of a Proteolysis-Targeting Chimera Degrader of JAK2 As a Potential Therapeutic Agent for JAK2-Mediated Myeloproliferative Neoplasms.

Caolin Wang, Ziqi Chen, Siyu Wang,Jie Wang, Panpan Yu, Chulu Huang, Yunpeng Wu,Zhenjiang Zhao, Wenyi Mei,Honglin Li,Lili Zhu

Journal of medicinal chemistry(2025)

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