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LC-MS/MS-Based Determination of Ambroxol in Human Plasma and Cerebrospinal Fluid: Validation and Applicability in Phase II Study on GBA-Associated Parkinson’s Disease Patients

Valentina Franco,Michela Palmisani, Fabiana Colucci,Rosa De Micco, Simone Aloisio, Federico Cazzaniga,Silvia Cerri,Francesca Crema, Francesca Dattrino,Barbara Garavaglia,Matteo Gastaldi, Pierfrancesco Mitrotti,Fabio Moda,Paola Rota, Rita Stiuso,Cristina Tassorelli,Roberto Eleopra,Alessandro Tessitore,Enza Maria Valente,Micol Avenali,Roberto Cilia

International Journal of Molecular Sciences（2025）

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Key words
plasma,cerebrospinal fluid,LC-MS/MS,ambroxol,Parkinson’s Disease,glucocerebrosidase
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