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    • Current Allergy and Clinical Immunology Journal

    Papers
    Chronic management of asthma - a paradigm shift
    Ismail S. Kalla
    Current Allergy and Clinical Immunology（2021）
    Asthma is a chronic inflammatory disorder of the airways in which many cells and cellular elements play a role. In the genetically susceptible individual this inflammation causes recurrent episodes of wheezing, breathlessness and cough, particularly at night and in the early morn...
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    Life-Threatening Asthma: Ventilatory Support In Paediatric Intensive Care
    S. Salie
    Current Allergy and Clinical Immunology（2016）
    The majority of children with acute severe asthma respond to emergency treatment with only a small proportion of children requiring paediatric intensive care (PICU) admission. Airway inflammation, oedema, excessive mucus secretion with airway plugging and bronchospasm results in ...
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    Inflammation, Immunity and Alzheimer'S Disease
    Marc Combrinck,John Joska
    Current Allergy and Clinical Immunology（2008）
    Alzheimer's disease (AD) is the commonest neuro-degenerative disorder of the elderly and results in progressive cognitive impairment. The main pathological features of the disease are the formation of extracellular amyloid plaques, intraneuronal neurofibrillary tangles and cerebr...
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    Severe Asthma Assessment and Management
    Sharon Kling
    Current Allergy and Clinical Immunology（2012）
    Around 5% of asthmatics have severe or difficult-to-control asthma, but they utilise a disproportionate amount of healthcare resources. Asthma that is not responding to treatment may be classified as 'problematic severe asthma', which is subcategorised into 'difficult-to-treat as...
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    A Pilot Study of Fungal Sensitisation in Patients with Allergic Rhinitis at the Ear, Nose and Throat Clinic at Universitas Academic Hospital, Bloemfontein
    C. W. R. Z. Borstlap,G. Joubert,R. Y. Seedat
    Current Allergy and Clinical Immunology（2014）
    The aim of this study was to determine the prevalence of sensitisation to moulds in patients with allergic rhinitis. Fifty consecutive patients with allergic rhinitis underwent skin prick tests to seven fungal allergen extracts. Thirty four percent of patients were sensitised to ...
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    Abc of allergy
    Shaunagh Emanuel,Di Hawarden
    Current Allergy and Clinical Immunology（2023）
    Dr Do-a-lot explores the topic of food allergy with her students. She gives them a broad overview of the subject: Prevalence and Epidemiology The prevalence of food allergy appears to be rising and it is a common problem encountered by the primary care physician. Commonly implica...
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    ATOPIC DERMATITIS - PREVENTION AND EDUCATION OF PATIENTS
    Robin J. Green,Adele Pentz
    Current Allergy and Clinical Immunology（2014）
    Why an article on prevention of atopic dermatitis and education of patients and their families? Well one might consider these two topics the two extremes of management of patients at risk from, or with, the condition. A physician might be called to intervene when families with ri...
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    Allergic Rhinoconjunctivitis in Athletes - Mechanisms of Impaired Performance and Implications for Management
    E. W. Derman,Di Hawarden,M. P. Schwellnus
    Current Allergy and Clinical Immunology（2010）
    Allergic rhinitis and conjunctivitis are the most common clinical manifestations of allergic disorders in the athletic population, and are probably under-diagnosed and under-treated in athletes. While some of the manifestations of allergic rhinitis are not difficult to diagnose, ...
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    A Primary Immunodeficiency Diseases Odyssey - Answer From The Exome In A Case With Immunodeficiency And Autoimmunity
    Brigitte Glanzmann, Nikola De Villiers,Marto Moller,Richard H. Glashoff,Rina Nortje,Britt-Sabina Petersen,Andre Franke,Mardelle Schoeman,Michael Urban,Craig J. Kinnear,Monika Esser
    Current Allergy and Clinical Immunology（2017）
    Objectives: To illustrate the use of whole exome sequencing (WES) in the diagnosis of an unidentified primary immunodeficiency disease (PID) with a complex clinical phenotype of severe infections and autoimmunity.Methods: Stored CNA from a 14-year-old deceased female of mixed rac...
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    The Wao White Book on Allergy 2011-2012
    Eugene G. Weinberg
    Current Allergy and Clinical Immunology（2011）
    The World Allergy Organization (WAO) White Book on Allergy presents an up-to-date review of the specialty of allergology from a global perspective. This book is of great importance and relevance for the practice of allergology in South Africa. It is of particular interest at this...
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    Dealing with the difficult patient
    Sharon Kling
    Current Allergy and Clinical Immunology（2024）
    Difficult patient encounters are relatively common in clinical practice. Most of the difficult encounters occur in the setting of chronic illness and/or mental illness, often with adjunctive factors such as poverty and other social problems. In paediatrics, the risk is that the c...
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    Novel Cross-Reactivity Syndrome: Severe Allergy To Ingested Quorn (Mycoprotein) In A Mould-Allergic Adolescent
    Claudia L. Gray
    Current Allergy and Clinical Immunology（2020）
    Cross-reactivities between aeroallergens and certain food allergens have long been recognised. The classical pattern is one of initial sensitisation to an inhalant allergen followed - usually years to decades later - by the development of a secondary food allergy, owing to shared...
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    The Role Of Bronchoscopy In Wheezing Preschool Children
    Pierre Goussard
    Current Allergy and Clinical Immunology（2018）
    Lower airway tract illnesses with wheeze are common in the preschool child and occur in approximately one-third of all children. Most children with preschool wheeze do not need further investigation, but referral is needed in the following cases: if the child does not respond to ...
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    Vulvar Conditions Where Allergy Plays A Role
    B Gerhard Lindeque
    Current Allergy and Clinical Immunology（2015）
    The vulvar skin in the adult comprises about one percent of the body surface and it is a highly specialised and adaptable skin. The competency of the vulvar and vaginal skin to withstand injury and infection is a remarkable feat of humankind. However, a number of allergic conditi...
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    MANAGEMENT OF CHILDREN WITH FOOD ALLERGIES IN SOUTH AFRICA: KNOWLEDGE AND PRACTICE OF PARENTS REGARDING PRECAUTIONARY ALLERGEN LABELLING - A CROSS-SECTIONAL SURVEY
    Tharien Bezuidenhout, Harris Steinmann,Daniel G. Nel,Evette van Niekerk
    Current Allergy and Clinical Immunology（2021）
    Background: The prevalence of precautionary allergen labelling (PAL) on food products is estimated at 65%, but PAL is inconsistently applied. Consumers believe that PAL is well regulated, but their knowledge and practice of PAL is unsound, which is inconsistent with their apparen...
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    ORAL ALLERGY SYNDROME - WHAT'S NEW
    Harris Steinman
    Current Allergy and Clinical Immunology（2009）
    Oral allergy syndrome/pollen-food syndrome (OAS/ PFS) affects up to 70% of patients with birch-pollen allergy. Prevalence is likely to continue to increase as the prevalence of inhalant allergies rises. Homologous proteins in fruits, vegetables, and pollens of grasses, trees and ...
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    Allergic Rhinitis And Asthma - Evidence For An Association
    Elizabeth Maleche Obimbo,Michael E. Levin
    Current Allergy and Clinical Immunology（2013）
    Asthma and allergic rhinitis (AR) are thought to be a reflection of the same disease process occurring in varying degrees along one continuous airway, and are often coexistent in the same individual. The evidence supporting this 'one airway' hypothesis is reviewed. Cohort and cas...
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