Design, Synthesis, and Biological Evaluation of Aminopyrazine Derivatives As Inhibitors of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MK-2).
Bioorganic & medicinal chemistry letters（2015）
Key words
MAPKAP kinase 2,MK-2,TNF alpha,Inflammation,Rheumatoid arthritis,Aminopyrazine,Guanidine,Thiourea replacement
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